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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Objectives |
|---|---|
| Topic 1: Regulatory and Clinical Research Concepts | - Clinical trial workflow
|
| Topic 2: Clinical Trials Data Standards | - CDISC Standards
|
| Topic 3: SAS Programming for Clinical Trials | - Reporting and Analysis
|
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
In a Statistical Analysis Plan (SAP) the following statement is written:
To test the association between the pain intensity reported by the patient and the treatment the patient has been administered, a Cochran-Mantel-Haenszel test will be performed adjusting for the country of the patient's investigational site.
The following variables and levels are used:
- Pain intensity (PAIN): "No pain", "Mild pain", "Moderate pain", "Severe pain", "Most severe pain"
- Treatment group (TREAT): "Placebo", "Drug A", "Drug B"
- Country (COUNTRY): Eight different values.
The following program is written to perform this analysis:
proc freq data=pain;
by COUNTRY;
tables PAIN * TREAT / cmh;
run;
This code does not produce the analysis requested by the SAP.
What is wrong with this code?
- A. The variable COUNTRY should be on the TABLES statement instead of the BY statement.
- B. The variable PAIN should be on the BY statement along with the variable COUNTRY.
- C. The variables PAIN and TREAT should be on the BY statement, and the variable COUNTRY should be on the TABLES statement.
- D. The option CMH should be on the PROC FREQ statement instead of on the TABLES statement.
Correct Answer: A 🗳️
The following SAS program is submitted:
If the value for the variable Subjcode is "WGT2", what is the value of the variable Description?
- A. Over
- B. Wgt2
- C. missing character value
- D. Unknown
Correct Answer: D 🗳️
You want to calculate the p-value of Fisher's exact test for a 3x3 table.
Which option must you add to the TABLES statement of PROC FREQ?
- A. EXPECTED
- B. CMH
- C. EXACT
- D. CHISQ
Correct Answer: C 🗳️
Review the following procedure code:
proc ttest data=DATA1;
class GROUPVAR1;
var VAR1;
run;
Which variable is most appropriate to be analyzed as variable VAR1?
- A. Age, with possible values of any integer between and including 18 and 65
- B. Systolic blood pressure, with possible values of "<120", "120 - 139", "140 - 159", "160 - 179", and
"180+" - C. Treatment, with possible values of "Placebo" or "Active"
- D. Number of infections, with possible values of 0, 1, or 2
Correct Answer: A 🗳️
The PROC COMPARE code below is intended to validate the results from a PROC FREQ.
Both the ProdFreqData and ValFreqData data sets contain 10 observations of the variable Frequency.
No other variables are present in these data sets.
proc compare base = ProdFreqData
comp = ValFreqData
out = FreqDiffs
outbase outcomp outdif outnoeq
method = exact
noprint;
run;
After successfully executing this PROC COMPARE step, what is a possible reason for the FreqDiffs file to contain 30 records?
- A. The internal values of Frequency are different in the base and comparison data sets.
- B. The variable types of Frequency are different in the base and comparison data sets.
- C. The variable labels of Frequency are different in the base and comparison data sets.
- D. The formatted values of Frequency are different in the base and comparison data sets.
Correct Answer: A 🗳️
Ira 
Maurice 
Zona 
Fitzgerald 
Hedy 
Harry 
Booth 
Viola 
Lionel 
Meredith 
Marico 
